3DPrinting.com presents the potential healing abilities of bioprinted skin.


The advancements in the field of regenerative medicine have been nothing short of remarkable. Our skin, the largest organ in the human body, possesses an amazing ability to heal itself. However, there are certain limitations, particularly for individuals with severe burns or inherited skin disorders. For years, scientists have been striving to replicate the complexity of human skin in a laboratory setting, and a recent breakthrough from Wake Forest University has brought us one step closer to that goal.

The team of researchers at Wake Forest University has developed a method to bioprint artificial skin using a combination of six different types of human skin cells. This bioink is then used to fabricate a three-layered artificial skin that closely resembles the architecture of natural skin. The significance of this accomplishment cannot be overstated.

When this bioprinted skin was transplanted into mice and pigs with skin injuries, the results were astonishing. The artificial skin quickly integrated with the host blood vessels, promoting faster healing and more naturally appearing outcomes. Additionally, the bioprinted skin was able to structure collagen, a critical component of natural skin, in a way that minimized scarring and facilitated wound healing.

Recreating the intricate multi-layered structure of human skin in a lab environment has proven to be a daunting task. However, the advent of 3D bioprinting technology has provided a promising solution. The ability to create “full thickness skin” using this method has the potential to revolutionize the field of regenerative medicine.

Dr. Anthony Atala, the lead researcher of this study, remarked, “These results show that the creation of full thickness human bioengineered skin is possible, and promotes quicker healing and more naturally appearing outcomes. Comprehensive skin healing is a significant clinical challenge, affecting millions of individuals worldwide, with limited options.”

This is not the first foray into bioprinting for Dr. Atala and his team. They have previously developed a skin bioprinter, and this recent study builds on their previous work by utilizing an expanded array of cell types to accurately capture the complexity of human skin.

Using a method known as 3D-extrusion printing, the team successfully printed the artificial skin and were able to maintain its integrity for over 52 days in a laboratory environment. This significant milestone brings us one step closer to the day when artificial skin can be used to heal severe burns and treat inherited skin disorders.

The implications of this research are far-reaching, and the potential to offer a more effective and natural solution for comprehensive skin healing is incredibly promising. As this field continues to advance, it is exciting to imagine a future where regenerative medicine technologies like bioprinting can revolutionize healthcare.

We would love to hear your thoughts on this groundbreaking research. Join the conversation on our Facebook, Twitter, and LinkedIn pages, and don’t forget to sign up for our weekly additive manufacturing newsletter to stay up to date with the latest stories in the field. Together, we can explore the possibilities of regenerative medicine and the exciting potential it holds for the future of healthcare.

Original source


“Why did the 3D printer go to therapy? Because it had too many layers of unresolved issues!”

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