Muscle tissues have been successfully 3D printed by researchers.


The Rise of 3D Printed Muscle Tissue: A Revolutionary Breakthrough in Medical Science

In recent years, the additive manufacturing industry has witnessed tremendous growth, propelling innovation across various professional domains. While the automotive and aerospace sectors have been at the forefront of adopting 3D printing technology, the medical field has also been quick to embrace this groundbreaking technology. And now, researchers at the esteemed Terasaki Institute for Biomedical Innovation have come up with an awe-inspiring application – the ability to produce and trial 3D printed muscle tissue.

Traditionally, when patients lose muscle tissue, a procedure called autologous transfer is performed. This entails taking healthy muscle mass from another part of the patient’s body to replace the missing tissue. However, this method has its own set of challenges and complications, including the risk of muscle loss in other areas of the body. Therefore, the researchers at the Terasaki Institute sought to create a viable alternative.

Their ingenious solution involves developing a bioink that closely mimics the natural formation of muscle tissue. This bioink comprises a hydrogel, myoblast cells, and microparticles. One key component is growth factor-1 (IGF-1), a hormone necessary for normal bone and tissue growth. The researchers used a gelatin-based hydrogel infused with myoblast cells and polylactic acid (PLGA) microparticles coated with IGF-1, which is continuously released.

The results were truly remarkable. Just three days after printing, the myoblast cells exhibited remarkable viability and began developing into complete synthetic muscle tissue over the course of ten days. This engineered tissue demonstrated independent movement, resembling real muscle. To validate its efficacy, the researchers implanted the cultured tissue into mice and observed its successful integration with the existing muscle mass.

3D printing muscle tissue represents a groundbreaking leap in the field of medicine. This innovative technology, by imitating the natural process of muscle formation, has the potential to revolutionize muscle mass replacement. However, it is important to note that additional clinical studies and testing are required to ensure the safe translation of this process to human patients. Nevertheless, the emergence of 3D printed muscle tissue heralds a promising future for medical advancements.

To learn more about the extensive research conducted by the Terasaki Institute, visit their website [insert link]. We would also love to hear your thoughts on 3D printed muscle tissue. Share your opinions and insights in the comments section below or join the conversation on our LinkedIn, Facebook, and Twitter pages. Additionally, remember to sign up for our free weekly Newsletter to stay updated with the latest news in 3D printing, delivered straight to your inbox. You can also explore our YouTube channel for informative videos.

*[Cover Photo Credits: de Barros et al./Terasaki Institute for Biomedical Innovation]*

Original source


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