[Source] In a groundbreaking development, researchers from the University of Oxford have used 3D printing technology to create engineered tissues that mimic the structure of the cerebral cortex. This new technique, called “droplet printing,” has the potential to revolutionize the treatment of brain injuries.
The researchers used human induced pluripotent stem cells (hiPSCs) to fabricate a two-layered brain tissue. These hiPSCs have the ability to generate most human cell types, making them an ideal material for this experiment. When implanted into mouse brain slices, the 3D-printed tissues showed both structural and functional integration.
Brain injuries can result in severe damage to the cerebral cortex, leading to difficulties in cognitive, motor, and communication skills. This new technique offers hope for tailored repairs to address these issues. Lead author Dr. Yongcheng Jin of Oxford’s Department of Chemistry expressed his excitement for this advance, stating that it is a significant step towards creating materials with the full structure and function of natural brain tissues.
The next step for the researchers is to enhance the technique and create more complex, multi-layered cerebral cortex tissues that closely resemble the brain’s architecture. In addition to repairing brain injuries, these engineered tissues may also prove beneficial in drug evaluation, cognitive studies, and brain development research.
The potential of this new technique has garnered attention from various sources, including the trending website NextShark. The researchers’ findings were recently published in the journal Nature Communications, further solidifying the importance of this breakthrough.
As the research progresses, there is hope that this technique could provide valuable insights into the workings of the human cortex. In the long term, it may also offer hope to individuals who sustain brain injuries, providing them with new opportunities for recovery and rehabilitation.
Overall, this development in 3D printing technology showcases the power of innovation and its potential to transform the field of medicine. With further advancements, we may eventually have the ability to create fully functional brain tissues, opening doors to new possibilities in neuroscience and patient care.
“Why did the 3D printer go to therapy? Because it had too many layers of unresolved issues!”
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